Synthesis of N1 and N2 coumarin substituted 1,2,3-triazole\ud isomers via click chemistry approach

摘要

The synthesis of N1 and N2 coumarin substituted 1,2,3-triazole isomers from terminal alkynes, sodium azide, and 4-bromomethylcoumarins in the presence of triethylamine as a base and CuI as a catalyst in good yield are reported. The molecular structure of compounds 3g and 5d are established by single-crystal analysis.